Higher-dose flu shot associated with lower Alzheimer's risk in study

The short version

• ScienceDaily reports UTHealth Houston researchers analyzed nearly 200,000 adults aged 65 and older.[ScienceDaily]
• Adults who received a high-dose flu vaccine showed a nearly 55% lower Alzheimer's risk, versus 40% for standard doses.[ScienceDaily]
• The findings, published in Neurology, show an association rather than cause and effect.[ScienceDaily]
• Alzheimer's is widespread, with over 7 million Americans aged 65 and older affected in 2025.[ScienceDaily]

Key facts

• UTHealth Houston researchers analyzed nearly 200,000 adults aged 65 and older.[ScienceDaily]
• Adults who received a high-dose influenza vaccine had a nearly 55% lower risk of developing Alzheimer's, compared with a 40% reduction previously associated with the standard-dose vaccine.[ScienceDaily]
• The findings were published in the medical journal Neurology.[ScienceDaily]
• In 2025, more than 7 million Americans aged 65 and older were living with Alzheimer's disease, about 1 in 9 people in that age group.[ScienceDaily]
• The researchers stated the findings demonstrate an association rather than establishing cause and effect.[ScienceDaily]

Sources

Outlet counts describe coverage, not independent confirmation. Reports may share a wire service or original source.

• Stronger flu shot linked to nearly 55% lower Alzheimer's riskScienceDaily - Health