Health
Amgen reports Imdelltra combination cut death risk 58% in lung cancer trial
CNBC reports that adding Amgen's Imdelltra to AstraZeneca's Imfinzi extended median survival in extensive-stage small cell lung cancer, according to Amgen.
The short version
- Amgen says adding Imdelltra to AstraZeneca's Imfinzi cut the risk of death by 58% in extensive-stage small cell lung cancer.[CNBC]
- Median overall survival reached 21.1 months with the combination versus 12.7 months with Imfinzi alone, and Amgen reported nearly 80% of patients were alive at one year versus 53%.[CNBC]
- The full results were presented at the European Society for Medical Oncology Congress, and the study did not test the combination against other first-line approaches.[CNBC]
Key facts
- Amgen stated that adding Imdelltra to Imfinzi reduced the risk of death by 58% in extensive-stage small cell lung cancer patients.[CNBC]
- The trial found median overall survival of 21.1 months with the combination compared with 12.7 months with Imfinzi alone.[CNBC]
- Amgen reported that nearly 80% of patients taking both drugs were alive at one year, compared with 53% receiving Imfinzi alone.[CNBC]
- The study was presented at the European Society for Medical Oncology Congress and did not test whether the combination was better than other first-line treatment approaches.[CNBC]
What remains uncertain
- The 58% risk reduction and survival figures are attributed to Amgen and have not been independently verified in the available reporting.[CNBC]
- Whether the combination is better than other first-line treatment approaches remains untested in this study.[CNBC]
- Only CNBC is reporting this event, so no second outlet corroborates the results.[CNBC]
Sources
Outlet counts describe coverage, not independent confirmation. Reports may share a wire service or original source.