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Chronic inflammation linked to structural heart changes in major UK study

ScienceDaily reports that high inflammation levels correlate with elevated risks of heart attack and stroke.

The short version

  • Researchers analyzed UK Biobank records covering nearly 480,000 adults using the inflammatory blood marker glycoprotein acetyls.[ScienceDaily]
  • Higher inflammation levels correlated with thicker heart walls, reduced chamber sizes, and impaired heart filling.[ScienceDaily]
  • Participants exhibiting the highest inflammation faced a 43% greater risk of suffering a heart attack or stroke.[ScienceDaily]
  • Experts suggest millions may unknowingly harbor inflammation that gradually alters heart anatomy prior to noticeable symptoms.[ScienceDaily]

Key facts

  • A study led by Imperial College London and the MRC Laboratory of Medical Sciences examined data from nearly 480,000 UK Biobank participants.[ScienceDaily]
  • The research measured inflammation levels through a blood biomarker called glycoprotein acetyls.[ScienceDaily]
  • Individuals with the highest inflammation levels exhibited a 43% higher risk of stroke and heart attack.[ScienceDaily]
  • High inflammation was associated with silent physical cardiac remodeling, including smaller heart chambers and thicker walls.[ScienceDaily]

What remains uncertain

  • The extent to which early anti-inflammatory treatments can directly prevent structural cardiac remodeling or avert heart failure remains subject to ongoing investigation.[ScienceDaily]

Sources

Outlet counts describe coverage, not independent confirmation. Reports may share a wire service or original source.