Health
Supercentenarian study reveals coexisting signs of advanced aging and biological youth
A study of 117-year-old Maria Branyas shows extreme longevity combines cellular wear with protective traits, according to ScienceDaily.
The short version
- A multi-omic analysis of Maria Branyas, who lived beyond age 117, identified markers of intense cellular aging alongside strong biological protection.[ScienceDaily]
- While Branyas possessed very short telomeres and aged immune cells, she maintained protective cardiovascular genetics and a younger epigenetic age.[ScienceDaily]
- Researchers emphasize that it remains too early to link these protective traits to individual lifestyle habits or choices.[ScienceDaily]
Key facts
- A comprehensive multi-omic study of Maria Branyas, who lived past 117 years, showed that extreme longevity can involve both advanced aging and biological protection.[ScienceDaily]
- The research group was led by Dr. Manel Esteller at the Josep Carreras Leukaemia Research Institute.[ScienceDaily]
- Branyas demonstrated markers of severe aging, including markedly shortened telomeres, an aged B lymphocyte profile, and pro-inflammatory immune traits.[ScienceDaily]
- The analysis revealed cardioprotective and neuroprotective genetic characteristics, low inflammation, and an epigenetic age younger than her chronological age.[ScienceDaily]
What remains uncertain
- Researchers caution that specific biological protections cannot yet be tied directly to particular behaviors or lifestyle choices.[ScienceDaily]
Sources
Outlet counts describe coverage, not independent confirmation. Reports may share a wire service or original source.
- Scientists find signs of extreme aging and youth in the same 117-year-oldScienceDaily - Health