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Moderna and Revolution Medicines advance novel cancer therapies following clinical milestones

Recent advances include positive melanoma vaccine trials and FDA approval of a molecular glue pill.

The short version

  • Moderna reported positive late-stage trial data for its personalized melanoma vaccine, while the FDA approved Revolution Medicines' molecular glue pill for late-stage prostate cancer.[Business Insider]
  • Neither treatment is a standalone cure; both are designed to accompany existing cancer treatments such as immunotherapy or chemotherapy.[Business Insider]
  • Moderna's vaccine remains pending FDA review with potential availability by 2027, while Revolution Medicines' pill carries a list price of around $40,000 monthly.[Business Insider]

Key facts

  • Moderna reported positive late-stage trial results for its personalized melanoma vaccine on August 19, causing its stock to surge 177%.[Business Insider]
  • The FDA approved Revolution Medicines' molecular glue drug, Rasonque, on August 26 to treat late-stage prostate cancer.[Business Insider]
  • Rasonque costs roughly $40,000 a month before insurance and is intended for use after chemotherapy.[Business Insider]
  • Moderna developed its vaccine technology through a $450 million collaboration with Merck.[Business Insider]

What remains uncertain

  • Moderna's melanoma vaccine is not yet approved by the FDA and its 2027 market availability depends on positive regulatory review.[Business Insider]

Sources

Outlet counts describe coverage, not independent confirmation. Reports may share a wire service or original source.