Japanese researchers find berry compound limits fat buildup in cultured muscle cells

The short version

• Researchers in Japan discovered that pterostilbene, a compound present in blueberries and grapes, reduced abnormal fat accumulation in cultured mouse muscle cells.[ScienceDaily]
• The compound works by stabilizing the PPARδ protein and preventing its degradation, which enhances fatty acid metabolism.[ScienceDaily]
• The findings are restricted to laboratory cell cultures and have not yet been evaluated for therapeutic effects in living animals or humans.[ScienceDaily]

Key facts

• Japanese scientists found that the dietary polyphenol pterostilbene helps cultured mouse muscle cells break down abnormal fat accumulations.[ScienceDaily]
• Pterostilbene stabilizes the PPARδ protein by halting its degradation through the ubiquitin-proteasome pathway.[ScienceDaily]
• Dr. Takakazu Mitani stated that there are currently no approved therapies designed specifically for myosteatosis.[ScienceDaily]

Sources

Outlet counts describe coverage, not independent confirmation. Reports may share a wire service or original source.

• Compound in blueberries may help muscle cells burn excess fatScienceDaily - Health