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Transplanted gene-edited pig kidney functions for record 285 days in patient

A woman has lived without dialysis for over nine months following an experimental xenotransplant.

The short version

  • A patient at Massachusetts General Hospital has lived without dialysis for over nine months with a gene-edited pig kidney, reaching 285 days of organ function.[Wired]
  • The milestone surpasses the previous xenotransplantation record of 271 days and marks the fifth recipient of an eGenesis pig kidney under the FDA's expanded access pathway.[Wired]
  • The FDA has cleared eGenesis to launch a formal clinical trial of up to 33 kidney failure patients beginning in 2027.[Wired]

Key facts

  • A patient at Massachusetts General Hospital has lived without dialysis for more than nine months with a gene-edited pig kidney.[Wired]
  • The pig kidney functioned for 285 days, breaking the prior record of 271 days set by Tim Andrews.[Wired]
  • The patient is the fifth individual to receive a genetically modified pig kidney from eGenesis via the FDA's expanded access pathway.[Wired]
  • Previous recipient Tim Andrews' pig kidney eventually failed due to tiny blood clots before he received a human transplant.[Wired]
  • The FDA approved eGenesis to conduct a formal trial in up to 33 patients aged 50 to 70 starting in 2027.[Wired]

What remains uncertain

  • The long-term durability of the transplanted pig kidney remains unknown, as organ rejection or clotting can occur at any time.[Wired]

Sources

Outlet counts describe coverage, not independent confirmation. Reports may share a wire service or original source.