← Latest briefing

Science

Researchers identify unique dual antibody gene system in vesper bats

A study shows over 500 bat species possess two sets of antibody heavy-chain genes, offering new insight into how bats tolerate severe viruses.

The short version

  • Scientists from Tulane University, Stanford University, and the CDC found that vesper bats possess two separate sets of antibody heavy-chain genes.
  • The genetic feature is unique among mammals, which typically have only a single set of these genes.
  • While the mechanism does not entirely explain bat viral resilience, researchers say it opens a new direction for understanding adaptive immunity and spillover risks.

Key facts

  • Vesper bats, a group comprising over 500 species across all continents except Antarctica, possess two separate sets of antibody heavy-chain genes.[ScienceDaily]
  • Every other known mammal possesses only a single set of antibody heavy-chain genes.[ScienceDaily]
  • The research was conducted by scientists at Tulane University, Stanford University, and the CDC, and was published in the journal Science Advances.[ScienceDaily]

What remains uncertain

  • The researchers noted that the dual gene system does not fully explain why bats serve as effective viral reservoirs without falling ill.[ScienceDaily]

Sources